Beyond the achievement of sustained virological response after liver transplantation
نویسندگان
چکیده
منابع مشابه
Hepatitis C reinfection after sustained virological response.
BACKGROUND & AIMS On-going risk behaviour can lead to hepatitis C virus (HCV) reinfection following successful treatment. We aimed to assess the incidence of persistent HCV reinfection in a population of people who inject drugs (PWID) who had achieved sustained virological response (SVR) seven years earlier. METHODS In 2004-2006 we conducted a multicentre treatment trial comprising HCV genoty...
متن کاملTreatment of recurrent genotype 4 hepatitis C after liver transplantation: early virological response is predictive of sustained virological response. An AISF RECOLT-C group study.
INTRODUCTION Hepatitis C virus genotype 4 is predominant in the Middle East and Northern Africa, even if it has recently spread to Southern Europe. Data about the treatment of post-liver transplantation (LT) genotype 4 hepatitis C recurrence are scarce. We report a retrospective analysis of post-LT genotype 4 hepatitis C treatment in 9 Italian transplant centres, focusing on the overall surviva...
متن کاملNonzero Risk of Hepatocellular Carcinoma Even after Sustained Virological Response
Approximately 130 to 150 million people are chronically infected with hepatitis C virus (HCV) in the world. HCV infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). The existence of hepatitis C— originally identifiable only as a type of non-A, non-B hepatitis— was suggested in the 1970s and proven in 1989. In the treatment of chronic hepatitis C (...
متن کاملSlower Fibrosis Progression Among Liver Transplant Recipients With Sustained Virological Response After Hepatitis C Treatment
BACKGROUND The natural course of hepatic fibrosis in HCV allograft recipients with sustained virological response (SVR) after anti-HCV therapy remains debatable. The aim of this study was to examine the progression of fibrosis in a cohort of patients who achieved SVR compared with those without treatment. METHODS The 167 patients who met the inclusion and exclusion criteria were chosen from a...
متن کاملQuantitative tests of liver function measure hepatic improvement after sustained virological response: results from the HALT-C trial.
BACKGROUND The impact of virologic response on hepatic function has not been previously defined. AIM To determine the relationships of quantitative liver function tests (QLFTs) with virological responses to peginterferon (PEG) +/- ribavirin (RBV) in patients with chronic hepatitis C and to use serial QLFTs to define the spectrum of hepatic improvement after sustained virological response (SVR...
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ژورنال
عنوان ژورنال: Liver International
سال: 2015
ISSN: 1478-3223
DOI: 10.1111/liv.12915